| 학회 |
한국재료학회 |
| 학술대회 |
2010년 가을 (11/11 ~ 11/12, 무주리조트) |
| 권호 |
16권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Synthesis and Characterization of Cross-linked PVA-Gelatin Hydrogel using Genipin Cross-linker for spongy bone applications |
| 초록 |
In this study, PVA-gelatin hydrogels were synthesized by 12 wt% polyvinyl alcohol solution and 30 wt% gelatin solution. 0.05 wt % genipin in PBS solution was employed as cross-linker agent. Degrees of cross-linking of hydrogels were determined by FT-IR spectrum. The highest compressive strength was 4.5 MPa with ratio of solutions PVA: gelatin: geinpin (1:1:1). MTT western blot analysis showed that crosslinked hydrogel was non-toxic and highly biocompatible. In vitro degradable of hydrogel showed that hydrogel could stable over one month. Hydrogels showed good MG-63 cell attachment through SEM morphology and confocal image. Thus, PVA-Gel hydrogel had high potential for bone applications such as spongy bone. |
| 저자 |
Nguyen Thi Hiep, Lee Byong-Taek
|
| 소속 |
Soonchunhyang Uni. |
| 키워드 |
PVA; Gelatin; Hydrogel
|
| E-Mail |
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