| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
생물공학_포스터 |
| 제목 |
Physiological reponse under various medium conditions of Escherichia coli, strain K-12 substr. W3110 |
| 초록 |
Glucose homeostasis is tightly controlled in all domains of life including bacteria, such as E. coli. A key regulatory point of glucose homeostasis resides in phosphosugar glucose-6-phosphate (G6P), generated during membrane translocation of glucose by the phosphotransferase system (PTS). Although the charged phosphate group is vital for retention of intracellular glucose, high levels of G6P are toxic to cells. Previous works suggested the mechanism for glucose homeostasis in E. coli with the small regulatory RNA SgrS and the haloacid dehalogenase (HAD)-like enzyme YigL. In this study, we want to decipher glucose homeostasis in E. coli, strain K-12 substr. W3110. This work will be expanded our knowledge for glucose homeostasis and understanding physiological implications depending on different genetic backgrounds. |
| 저자 |
김성경1, 임재형1, 정규열2
|
| 소속 |
1POSTECH Chemical Engineering, 2POSTECH Chemical Engineering / POSTECH I-bio |
| 키워드 |
phosphosugar stress; small non-coding RNA; phosphotransferase system
|
| E-Mail |
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