| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Metal Ion-Complexed Zwitterionic Polymeric Additives for Implantable Medical Devices |
| 초록 |
Thrombus formation and infection by implantable medical device still have been unsolved problems. Here, we designed a series of metal ion-complexed zwitterionic polyurethane (m-zPU) additives to confer anti-thrombogenic and anti-microbial activities to polyvinyl chloride (PVC). Metal ions including Ag, Cu, Zn and Ce, were selected as candidates for complexation with zwitterionic polymer. Our results demonstrate that addition of m-zPU significantly lower protein adsorption and larger zone of bacterial inhibition than pure PVC. These results suggest the m-zPU would be useful for implantable medical devices. |
| 저자 |
최수연1, 가동헌1, 강종희1, 고원건2, 정윤기1
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| 소속 |
1한국과학기술(연), 2연세대 |
| 키워드 |
polymeric additive; zwitterion; metal ion; anti-microbial; anti-thrombogenic; implantable medical device
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| E-Mail |
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