화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 생체재료_포스터
제목 Evaluation of Osteogenesis of Photo-immobilized BMP-2 using Azido-phenyl Gelatin on a collagen sheet Using Rat Calvarial Defect Model
초록 The collagen, as a natural polymer, has good biocompatibility, easily degraded into physiologically compatible product and is suitable for interaction with cells. Therefore, large variety collagen formulations has received much attention in medical and tissue engineering filed. As a preliminary study, we photo-immobilize the BMP-2 on a collagen sheet with an UV-light reactive azidophenly gelatin (Az-gel), and determine the optimal density of Az-gel and UV treatment time. The purpose of this study is to confirm the usefulness of photo reactive Az-gel on collagen sheet for the BMP-2 as a carrier in the rat calvarial defect animal model.

Acknowledgements    
This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and future Planning (No. NRF-2014R1A2A1A11052623)
저자 정진홍, 함대웅, 김은혜, 한가득, 노승현, 김재원, 송광섭, 손태일
소속 중앙대
키워드 Azido-phenyl Gelatin; BMP-2; photo-immobilization; Rat Calvarial Defect Model
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