| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_생체재료 |
| 제목 |
Cellular surface-modified scaffolds for delivery of nephron progenitor cell for renal tissue regeneration |
| 초록 |
Reneal tissue regeneration is expected to be a promising strategy, in context of currently limmited treatment and organ donation for cronic kideny disese. In recent year, extracellular matrix (ECM) derived scaffold, owing to its highly biocompatiblity and ability to guid renel tissue regeneration, have been widely investigated to treat kidney regeneration. In our previous study, magnesium hydroxide nanoparticles incorporated three dimensional porous PLGA scaffold was directly coated with fibroblast derived extracellular matrix. Inspired from previous study, here we have prepared nephron progenitor cell containing ECM surface- modified scaffolds for renal tissue regeneration. In in vitro cell studies with NPCs, modified scaffold showed improved cell viability and significantly increased growth factor release in respective time. |
| 저자 |
Md Lemon Hasan1, 김윤아2, So Young Chun3, Seung Kwon You4, Tae Gyun Kwon3, Dong Keun Han5, Won-Gun Koh6, 정윤기7
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| 소속 |
1Korea Institute of Science and Technology, 2Korea Institute of Science and Technology / Yonsei Univ., 3Kyungpook national Univ., 4Korea Univ., 5Cha Univ., 6Yonsei Univ., 7한국과학기술(연) |
| 키워드 |
: renal tissue regeneration; porous scaffold; decellularized extracellular matrix.
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| E-Mail |
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