화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU))
권호 26권 1호
발표분야 포스터-생체재료
제목 Alginate Encapsulation of Mesenchymal Stem Cell 3D cultured spheroids for Treatment of Inflammatory Bowel Disease
초록 Alginate Encapsulation of Mesenchymal Stem Cell 3D cultured spheroids for Treatment of Inflammatory Bowel DiseaseJunhyeung Park

School of Medicine, Sungkyunkwan University Natural Sciences Campus 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, Korea

Currently, mesenchymal stem cell (MSC)-based therapy offers a promise for the given conditions. This study was aimed at developing a robust method of alginate encapsulation of MSC spheroids, namely “Surface triggering in situ gelation (STIG)”, for the treatment of chronic inflammatory bowel disease (IBD). Alginate encapsulation of spheroids was performed following protocol. Briefly, The conjugated MSC spheroids with calcium carbonate microspheres were incubated with the solution of alginate. As a result our method of alginate encapsulation of spheroids may offer a huge promise to enhance MSC functionality for effective treatment of IBD and other diseases.
저자 박준형, 정지헌
소속 성균관대
키워드 Mesenchymal stem cell; alginate; Inflammatory Bowel Disease
E-Mail