화학공학소재연구정보센터
학회 한국재료학회
학술대회 2008년 가을 (11/07 ~ 11/07, 차세대융합기술연구원)
권호 14권 2호
발표분야 나노생체재료
제목 Evaluation of Mechanical properties of Bi-Layer Artificial Blood Vessel Made by PCL/Chitosan Composite by Electrospinning
초록 Artificial blood vessel was fabricated by bi-layer method from poly caprolactone (PCL) (inner layer) and chitosan (outer layer) by electrospinning. With high surface to volume ratio and porosity of polymer electrospun nanofibers were thought to mimic natural extra cellular matrix (ECM) and thus promoted cell adhesion, migration and proliferation. Mechanical of samples increased after crosslinking chitosan layer by glutaraldehyde. Relationship of mechanical properties, inner/outer diameter and thickness of tubes were characterized. Morphology of nanofiber and small-diameter was conformed by SEM image. FT-IR data showed that chitosan was crosslinked by glutaraldehyde.
저자 Thi-Hiep Nguyen, Hun-Mo Yang, Ho-Yeon Song, Byong-Taek Lee
소속 Soonchunhyang Univ.
키워드 PCL; Chitosan; Electro spinning; Mechanical
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