| 초록 |
Melanins, among which the black brown eumelanin and the redish pheomelanin, are ubiquitous and multifunctional pigments among living organisms. They may present interesting applications in biolelectronics and for biomedical applications but to reach improved properties, a more fundamental knowledge of their self assembly, from oxidized catacholamines, is mandatory. In this presentation the results of molecular dynamics simulations allowing to describe the structure of eumelanin from the self assembly of the most stable tetramer of 5,6 hydroxyindole will be presented. This in silico eumelanin has structural mechanical and optical properties in excellent agreement with dopamine-melanin (Figure). High resolution TEM also revealed the presence of graphite like domains, a knowledge we are now intensively exploiting for a better control of electrical conductivity of eumelanin. In addition it will be shown that a templated synthesis of eumelanin in the presence of surfactants or proteins allows to produce pretty monodispersed nanoparticles. Finally, the deposition mechanism of eumelanin films on solid surfaces as well as some properties and applications of those films will be presented. |
