| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Silver Nanoparticles embedded in polyaspartamide-based hydrogels for biomedical applications |
| 초록 |
The increased use of medical devices combined with the emergence of new multi-drug resistant bacteria has focused the research on biomaterials-related infections. Silver has already been proven to be effective against bacterial infections even at low concentration (0.1-10 ppm). Furthermore, it has been demonstrated that nano-particulate (NP) silver could be even more efficient due to a better interaction with bacteria and a long-lasting activity compared to ionic silver. Polyaspartamides are very promising for biomedical applications owing to their water-solubility, nontoxicity, nonantigenicity, and biodegradability. In this work, DOPA-conjugated polyaspartamide was synthesized and used to prepare the crosslinked gel via catechol-boron coordinative interactions. The adsorbed silver ion onto the remaining catechol moieties within the gel matrix will be reduced in-situ by redox process to provide the silver NP-embedded hydrogel. |
| 저자 |
김지흥1, Wang Bo1, Milene Tan1, K. M. Fromm2
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| 소속 |
1성균관대, 2Univ. of Fribourg |
| 키워드 |
Silver nanoparticle; hydrogel; dopamine; polyaspartamide
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| E-Mail |
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