| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_생체재료 |
| 제목 |
Multifunctional Drug-eluting Beads Capable of X-ray Imaging and pH Neutralization for Effective Transcatheter Chemoembolization |
| 초록 |
Transcatheter arterial chemoembolization (TACE) is the most commonly used interventional procedure to treat inoperable hepatocellular carcinoma (HCC). It treats tumors by administering embolic materials with anticancer drugs to the hepatic artery. Drug-eluting beads (DEBs) have been used in the TACE. However, since the existing DEB has no imaging capability, contrast agents must be used in the procedure, and it is difficult to check the progress after the procedure. Also, the acidic micro-environment induced by the embolization of blood vessels causes recurrence and metastasis. In this study, we developed multifunctional DEBs capable of X-ray imaging and pH neutralization for effective transcatheter chemoembolization. In vitro, X-ray imaging, and pH neutralization experiments were conducted to evaluate the functionality of prepared DEBs. |
| 저자 |
김준규, 김대환, 백승운, 김다슬, 한동근, 박우람
|
| 소속 |
차의과학대 |
| 키워드 |
Hepatocelluar carcinoma (HCC); Transcatheter arterial chemoembolization (TACE); X-ray imaging; Acidic tumor microenvironment; pH neutralization
|
| E-Mail |
|
