화학공학소재연구정보센터
학회 한국재료학회
학술대회 2010년 가을 (11/11 ~ 11/12, 무주리조트)
권호 16권 2호
발표분야 D. Health and Biological Materials(생체 및 의용재료)
제목 Fabrication and characterization of aligned Gelatin/HAp composites scaffolds for bone tissue engineering
초록 Recently, the electrospinning technique has been used to fabricate fibrous mat for biomedical applications such as artificial blood vessel, drug release and tissue engineering scaffolds etc. because this method is simple and easy to get ultrafine polymer fibers. Depending on the speed of rotating drum collector, fiber alignment was different. In this work, Gelatin fibers were aligned by electrospinnning machine. For inducing bone regeneration, HAp nanopowders were loaded in the gelatin fibers with different content variation. The mechanical properties like tensile strength of the Gelatin/HAp composites scaffolds were evaluated. Microstructure and morphological evaluation were carried out by SEM technique. Phase characterization was performed by XRD and FT-IR. Detailed bio-compatibility of the material system and the influence of the structural feature on cell proliferation were evaluated MG- 63 osteoblasts like cell culture on the fabricated material.
저자 Yang-Hee Kim1, Hun-Mo Yang2, Byong-Taek Lee3
소속 1Department of Biomedical Engineering and Materials, 2Soonchunghyang Univ., 3Department of Physiology
키워드 Gelatin; HAp; electrospinning; alignment
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