화학공학소재연구정보센터
학회 한국재료학회
학술대회 2010년 가을 (11/11 ~ 11/12, 무주리조트)
권호 16권 2호
발표분야 D. Health and Biological Materials(생체 및 의용재료)
제목 Improvement of Mechanical Properties of Calcium Phosphate-Calcium Sulfate Injectable Bone Substitute Using microwave sintered TTCP powder
초록 In this study, citric acid, chitosan, and hydroxyl propyl methyl cellulose (HPMC) were used as the liquid phase and tetra calcium phosphate (TTCP), dicalcium phosphate dehydrate (DCPD) and calcium sulfate dehydrate (CSD, CaSO4 . 2H2O) powders as the solid phase. The conversional synthesis method of TTCP used furnace heating of DCPD and CSD on solid phase. In this work, microwave irradiated to synthesis the powders and the differences were invastigated. There were following three groups. Each group was holding the percentage of chitosan and citric acid (chitosan 2%, citric acid 20%). Only the HPMC percentage was changed to 2 wt%, 3 wt% and 4 wt%. Setting time was measured depending on HPMC Percentage. IBS was incubated at 37℃ in 100% humidity prior to characterization. Material properties like   compressive strength and porosity were investigated. Microstructure and morphology were investigated by SEM & XRD. Bio-compatibility was investigated by MTT assay and One-cell morphology.
저자 Hae-In Lee1, Yang-Hee Kim2, Byong-Taek Lee3
소속 1Department of Biomedical Engineering and Materials, 2College of Medicine, 3Soonchunhyang Univ.
키워드 Calcium phosphate; Bone cement; Injectable bone substitute; MTT assay
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