| 초록 |
Wound dressing has been treated in order to protect the wound site that have facility including absorbing exudate, accelerating wound recovery, and etc. In this work, porous polyester fabrics were rendered to have Janus property via initiated chemical vapor deposition (iCVD) of a fluoropolymer for being applied as wound dressing. Antimicrobial property of hydrophobic surface was confirmed by bacterial cell growth reduction analysis. Simple hydrolysis reaction with KOH on the fluoropolymer resulted in hydrophilic carboxylic acid functionality, which was further chemically reacted to immobilize photo-crosslinkable gelatin methacrylate (GelMA). The Janus fabrics with macroporous structure allowed excess exudate to be evaporated, which can further control the moist environments at wound sites. In conclusion, as all-in-one system, the Janus polyester fabrics containing antimicrobial, water-repellent properties and immobilized hydrogel would be applied to skin wound regeneration. |
