화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2014년 가을 (10/22 ~ 10/24, 대전 DCC)
권호 20권 2호, p.1572
발표분야 생물화공
제목 Metabolic engineering of Corynebacterium glutamicum for the production of bio-nylon precursor
초록 Biomass-based plastics are a promising and inevitable alternatives to petroleum-based plastics. Cadaverine, which is a C5 diamine, attracts scientific and industrial attention since it can be used as a precursor of bio-based nylons such as nylon 5.4, nylon 5.6 and nylon 5.10. It can be produced from L-lysine by an enzymatic reaction of L-lysine decarboxylase (LDC). In this study, a L-lysine hyper producing strain of Corynebacterium glutamicum was engineered to produce cadaverine by expressing the E. coli cadA gene, which is the most studied LDC for the conversion of L-lysine into cadaverine, with different synthetic promoters. Detailed results will be presented in this presentation.
저자 최재우1, 김은영1, 오영훈1, 송봉근1, 박시재2, 이승환1
소속 1한국화학(연), 2명지대
키워드 biomass-based plastic
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