| 초록 |
Bisphenol A (BPA) is a highly hazardous and carcinogenic compound, especially to infants. For efficient prevention of exposure to BPA, therefore, there is an urgent technological need to develop a novel detection means with high sensitivity and selectivity. To meet this goal, in the present work, we propose an electrochemical detection system based on a sensing platform comprising layer-by-layer assembled reduced graphene oxide (rGO) electrode and surface-immobilized probes of recombinant protein of Lac repressor (LacI). Electrochemical impedance spectroscopy (EIS) was conducted to confirm the feasibility of the present system as an impedimetric sensor. It showed a minimum detection limit down to 5.0 fM. To confirm the selectivity of the screened peptide sequence, BPA analogues such as Bisphenol S (BPS) and Bisphenol F (BPF) were also assessed. |
