| 초록 |
The biocompatibilty of materials is decided by the surface properties including hydrophobicity/hydrophilicity. Hydrophilic surfaces or PEO-grafted surfaces are known to suppress protein or cell adhesion. In this study, PEO or PEO-SO3 was grafted onto polymers by UV irradiation utilizing photoactive azide end group. The surfaces photo-grafted by PEO or PEO-SO3 were characterized by the dynamic contact angle measurement and ESCA analysis. In addition, the surface morphology of PEO or PEO-SO3 grafted surface was investigated by AFM. The protein and cell adsorption studies were conducted on the modified surfaces to examine the effect of PEO or PEO-SO3 groups grafted. QCM-D (quartz crystal microbalance with dissipation monitoring) method was introduced for studying protein adsorption. The modified surfaces exhibited the increased hydrophilicy and decreased protein and cell adsorption. However, the surface grafted with PEO-SO3 exhibited a specific affinity for albumin |
