| 초록 |
Cellulose nanofibrils (CNFs) have recently gained much attention as biomedical application materials due to their outstanding biocompatibility and biodegradability. In order to take advantage of CNFs, we physically mixed the TEMPO-treated cellulose nanofibrils (TCNF) with metal salt solutions, which could overcome the weak mechanical strength of TCNF by forming the metal-carboxylate coordination bonding as sacrificial bonds. The structural deformation and reversibility of the TCNF hydrogels are affected by the valency number of the metal cations. In addition, we confirmed that the TCNFs with metal cations were highly biocompatible. We used large amplitude oscillatory shear (LAOS) test to investigate the nonlinear inter-cycle and intra-cycle viscoelastic responses of these TCNF hydrogels, and the sequence of physical processes (SPP) analysis to characterize the transient structural and rheological behaviors. |
