| 학회 | 한국화학공학회 |
| 학술대회 | 2022년 봄 (04/20 ~ 04/23, 제주국제컨벤션센터) |
| 권호 | 28권 1호, p.1043 |
| 발표분야 | [주제 12] 화학공학일반(부문위원회 발표) |
| 제목 | Design of Ceramide Carriers via Liquid Crystalline Microdroplets |
| 초록 | Ceramides, which compose skin barrier, play a crucial role in preventing skin dehydration. Thus, supplying much of ceramides to skin is a major goal in cosmetic applications. To contain ceramides in cosmetics, lyotropic liquid crystals (LLCs) were used as a carrier. However, hydrogen bonds and hydrophobicity of ceramides, which cause crystallization in aqueous solutions, limit the content of ceramides.(<1%) Also, LLC carriers in aqueous solutions are not intrinsically unstable due to their hydrophilic nature. Here, to overcome the previous limitations, we propose a cholesteric thermotropic liquid crystals (CLCs) carrier that have biocompatible and hydrophobic nature. We demonstrate that the presence of hydrophobic (CLC)-hydrophilic (aqueous solution) interface enables the self-assembly of ceramides at the interface, thus significantly increasing the concentration of ceramides in the microdroplet carriers. This work was supported by COSMAX Inc. |
| 저자 | 최영선, 김혜인, 오광석, 김영기 |
| 소속 | 포항공과대 |
| 키워드 | 재료(Materials) |
| 원문파일 | 초록 보기 |
