| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-에너지저장·변환 |
| 제목 |
Naphthoquinone as a potential colorimetric and fluorescence chemosensor for sensing of Fe2+ ion: Its application in bio-imaging of live cells and zebrafish |
| 초록 |
A new naphthoquinone-based chemosensor 2HPN for the selective detection of Fe2+ ion has been developed. The sensing property of the chemosensor 2HPN was evaluated in aqueous acetonitrile (CH3CN) medium by a fluorescence emission method. The metal binding studies of ligand 2HPN showed selective “turn-on” fluorescence responses for Fe2+ ion (Ka = 1.0 × 106 M-1). The detection limit of the ligand 2HPN to Fe2+ was calculated to be 0.272 µM, which is lower than the WHO recommendation in drinking water. Significantly, the obtained chemosensor 2HPN it the ability to sense Fe2+ via naked-eye detection over various metal ions. The chemosensor operated through the intramolecular charge transfer (ICT) mechanism that was further supported by FT-IR analysis, NMR titrations, and DFT calculations. The efficiency of the chemosensor 2HPN as a biomarker for Fe2+ was successfully demonstrated by bio-imaging of human cancer cells and zebrafish. |
| 저자 |
Palanisamy Ravichandiran, 유동진
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| 소속 |
전북대 |
| 키워드 |
Quinone; colorimetric sensor; cancer cells
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| E-Mail |
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