화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 생물공학
제목 Cloning and characterization of putative soluble epoxide hydrolase of Zebra fish
초록 Chiral epoxides can be used as synthetic building blocks for preparing more complex chiral pharmaceuticals. Chiral epoxides can be produced by epoxide hydrolase (EH)-catalyzed kinetic resolution of racemic epoxide substrates. In this study, a soluble EH gene was cloned from zebra fish on the basis of data-mining of genomic database. The gene was expressed in Escherichia coli. Zebra fish soluble EH was evaluated for its ability to produce chiral styrene oxide.
저자 이은열1, 최성희2, 김희숙2
소속 1경희대, 2경성대
키워드 zebra fish; epoxide hydrolase; soluble epoxide hydrolase; cloning
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