| 초록 |
Cell membranes are selectively permeable to ions, which is essential for cellular survival. The control of ion permeability is delicately regulated by ion channels, wherein ion-binding motifs are located in a row, providing a continuous pathway for ions to selectively pass through the cell membranes. Because the selective ion channels are highly applicable to diverse fields ranging from fundamental membrane studies to development of ultra-selective biosensors, there have been ceaseless efforts to artificially create the ion channels. In this work, by mimicking the cell membranes in nature, we successfully created ion-selective artificial membranes that contain molecular recognition-based synthetic channels. As the selective permeability system was composed of a freestanding lipid bilayer, ion-binding nucleic acid nanostructure, and hydrophobic anchor for lipid incorporation, it preferentially transported potassium ions among diverse metal ions. |
