| 학회 | 한국공업화학회 |
| 학술대회 | 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 19권 2호 |
| 발표분야 | 콜로이드계면화학_포스터 |
| 제목 | Intratympanic delivery of oligoarginine-conjugated nanoparticles for treating inner ear disease |
| 초록 | Hearing loss is a major public health problem, and its treatment with traditional therapy strategies is often unsuccessful due to limited drug access in the cochlea cell. In the previous study, we synthesized poly(2-hydroxyethyl aspartamide)(PHEA)-grafted with octadecyl amine (C18) to apply for drug delivery into ear. However, the low biomembrane permeability of the polymer was generally considered to be limiting factor in successful delivery of the cochlea. |
| 저자 | 김종득, 윤지영 |
| 소속 | 한국과학기술원 |
| 키워드 | drug delivery system; inner ear therapy |
