| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
의료용고분자 부문위원회 |
| 제목 |
Charactarization of Thermosensitive Hydrogel based on Chitosan and Pluronic F-127 for Adhesion barrier |
| 초록 |
Tissue adhesions occur after infection or surgical treatment, most frequently of peritoneum and pelvis. We prepared thermosensitive hydrogel based on chitosan and pluronic F-127 for adhesion barrier. The aim of the this study was to examined the preparation and characterization of hydrogel formulation composed of pluronic and chitosan.The physicochemical properties of hydrogel were analyzed by gelation time and temperature, viscocity, antimicrobial and scanning electron microscope (SEM) measurement. Also, invitro experiments correspond well with invivo observations on tissue adhesions. Therefore, the chitosan/pluronic hydrogel may be the potential to prevent postsurgical adhesions in clinical state. |
| 저자 |
손동희1, 남정표1, 박준규1, 김원석1, 최창용2, 박영훈1, 장미경1, 나재운1
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| 소속 |
1순천대, 2다이나믹 |
| 키워드 |
adhesion barrier; chitosan; pluronic; hydrogel
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| E-Mail |
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