초록 |
Advanced technologies that can mimic hierarchical architectures found in nature can provide pivotal clues for elucidating numerous biological mechanisms. Herein, a novel technology, spontaneous organization of multi-layer generation by electrospray using organic salts, was developed to create self-assembled fibrous structures. The simple inclusion of organic salts in a polymer solution prior to electrospraying was key to mediating the structural versatilities of the fibrous structures. The multi-layered matrix demonstrated great potential as a crucial building block capable of inducing sequential, localized drug delivery or orchestrating cellular distribution in vivo, thereby expanding its scope of use to cover a variety of biomedical applications. |