| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Gelatin microspheres with tunable surface properties: Versatile nutrient carrier for production of cost-effective cultured meat |
| 초록 |
Cultured meat is artificial meat obtained by cell culture based on cell engineering technology without unethical slaughter. High production costs due to excessive use of animal-derived serum are putting the brakes on the popularization of cultured meat. Herein, we report on a strategy to develop eco-friendly cultured meat based on myoblast sheet containing fish gelatin microsphere (GMS). The edible GMSs show various morphologies and binding activities depending on the degree of crosslinking. Insulin-like growth factor 1 and blue algae extract were selected as reasonable nutrients used in serum-reduced growth medium. We have incorporated these nutrients into GMSs with different surface properties and analyzed the loading and release behaviors of nutrients for each GMS. GMSs applied to cell sheet culture created cost- and time-effective cell sheets with meat shapes by exhibiting four functions. Finally, we developed cost-effective cultured meat models composed of GMS-based cell sheets. |
| 저자 |
박소현, 한의영, 허지웅, 조성은, 홍진기
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| 소속 |
연세대 |
| 키워드 |
Gelatin; microstructure; morphology; controlled release; cultured meat; cost-efficiency
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| E-Mail |
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