화학공학소재연구정보센터
학회 한국재료학회
학술대회 2013년 가을 (11/06 ~ 11/08, 제주롯데호텔)
권호 19권 2호
발표분야 D. 바이오재료(Biomaterials)
제목 Fabrication and characterization of novel hydrogel scaffold of Oxidized alginate, gelatin and blood serum loaded with BCP particles for bone tissue regeneration
초록 In this work, oxidized alginate, gelatin and blood serum based novel hydrogel system that loaded with BCP particle was fabricated with various ratio maintaining the gradual increasing amount of blood serum (0%, 5%, 10% and 15%) which in turn focus to the characterization of the system that lead to the optimum composition. Here oxidized alginate had resulted in situ cross linking with blood serum collected from rat and gelatin. Fabricated samples were undergone scanning electron microscopy (SEM), porosity meter, XRD, compressive strength, FTIR and NMR investigation to observe the structure, surface morphology, mechanical strength and degradation. In vitro work was composed of cell attachment, cell viability, cell proliferation and cell differentiation. Loading of blood serum of 5% had shown significant up rise over the in vitro result.
저자 Kallyanashis Paul1, Nguyen Thuy Ba Linh2, Young-Ki Min3, Byong Taek Lee1
소속 1Department of Regenerative Medicine, 2College of Medicine, 3Soonchunhyang Univ.
키워드 Oxidized alginate; blood serum; BCP particle
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