| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
(콜로이드계면화학)첨단 소재 및 바이오 기술 분야의 표면화학 연구동향 |
| 제목 |
Electrochemical surface modification of bioelectrodes using hyaluronic acid for improved biocompatibility |
| 초록 |
Bioelectrodes that can mediate electrical signals with living system have been widely used for biosensor, prosthetic probes, etc. However, the electrical properties of bioelectrodes are commonly impaired in the biological environment due to biofouling of the bioelectrode surfaces. Hence, the development of facile and effective surface modification of bioelectrodes is highly required. In this study, we chemically modified biocompatible hyaluronic acid with dopamine (DA-HA) and employed it for electrochemical electrode modification. The modified electrodes exhibit highly hydrophilic surfaces and strong coating adhesion. Besides, the electrochemical impedance of the DA-HA-modified electrodes maintains similar to bare electrodes. Furthermore, DA-HA-modified electrodes could minimize adhesion of fibroblasts and alleviate the scar tissue formation in vivo. In conclusion, our novel electrochemical passivation of electrodes using DA-HA can improve biocompatibility of bioelectrodes. |
| 저자 |
이재영1, 김세민2
|
| 소속 |
1광주과학기술원 신소재공학부 / 광주과학기술원 의생명공학과, 2광주과학기술원 신소재공학부 |
| 키워드 |
bioelectrode; antifouling; electrochemistry
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| E-Mail |
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