화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2022년 봄 (04/20 ~ 04/23, 제주국제컨벤션센터)
권호 28권 1호, p.1228
발표분야 [주제 12] 화학공학일반(부문위원회 발표)
제목 Construction of pesticides recovering Escherichia coli through the cell surface display of binding peptide
초록 Fenitrothion, or O, O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate, is a nitrophenolic pesticide that has been widely used in agriculture. The inhibition of acetylcholine esterase activity and inhibition of acetylcholine breakdown in synapses result in the accumulation of acetylcholine in synapses, which causes convulsions, paralysis, and death of insects. However, under aerobic conditions, the major hydrolysis metabolite of fenitrothion, 3-methyl-4-nitrophenol, is toxic to many living organisms, raising environmental safety concerns. In this study, fenitrothion-adsorbing recombinant Escherichia coli was constructed through the display of pesticide-binding peptide, using OmpC as an anchoring motif.
저자 정재훈, Kumaravel Ashokkumar, 홍순호
소속 울산대
키워드 생물화공(Biochemical Engineering)
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