| 학회 |
한국고분자학회 |
| 학술대회 |
2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
47권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Rapidly-curable surgical glues enforced by adjustable multilength networks |
| 초록 |
Recently, surgical adhesives are used in various medical fields as a promising potential for sutureless wound closures. Nevertheless, existing limitations of conventional medical glues including variable adhesions in wet conditions, improper mechanical properties, and toxicity hindered its application on ocular surface. In this study, we developed photocrosslinkable hyaluronic acid (HA) with multilength networks enabling adjustment of properties. Mechanical and adhesive properties were adjusted by introducing short and long crosslinkable groups. In the in vivo test, the HA glue sealed the wound area within 5 seconds and exhibited enhanced healing efficiency by a firm water-tight seal compared to the control without compromising safety issues (low-energy curing light) and transparency. |
| 저자 |
이혜선, Ajeesh Chandrasekharan, 성금용, 조연지, 이종수, 양승윤
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| 소속 |
부산대 |
| 키워드 |
tissue adhesive; hyaluronic acid; biopolymer; wound healing
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| E-Mail |
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