| 학회 | 한국화학공학회 |
| 학술대회 | 2009년 가을 (10/22 ~ 10/23, 일산 KINTEX) |
| 권호 | 15권 2호, p.1560 |
| 발표분야 | 분리기술 |
| 제목 | Chiral recognition of mandelic acid by L-MA derivatives modified sensor using quartz crystal microbalance in liquid environment |
| 초록 | This study presents a new method for the selective recognition of chiral mandelic acid (MA) using of an L-Mandelic acid (L-MA) derivatives as the selector in liquid environment. The proposed method is based on quartzcrystal microbalance (QCM) detection, integrated with a molecular self-assembly reaction technique in liquid phase. The construction of the L-MA derivatives-modified QCM sensor involved a two-step assembly procedure. The chiral recognizability of L-MA and D-MA on the L-MA derivatives-modified surface was then examined using QCM in liquid phase. The chiral discrimination factor α between L-MA and D-MA detected by QCM was found to be about 6.0. An atomic force microscope (AFM) technique is used to confirm the procedure of the chiral recognizability of L-MA and D-MA on the L-MA derivatives-modified surface. The L-MA derivatives-modified QCM sensor showed good stability and reusability. The present chiral recognition results suggest that L-MA derivatives from acylation reaction is an excellent resolving agent for the resolution of chiral mandelic acid. |
| 저자 | Li Fang1, 김종민2, 장상목2, 김우식1 |
| 소속 | 1경희대, 2동아대 |
| 키워드 | Chiral recognition; Mandelic acid; Mandelic acid derivatives; Quartz crystal microbalance; Molecular self-assembly |
| 원문파일 | 초록 보기 |
