초록 |
Layer-by-layer deposition (LbL) is a versatile technique whereby ultrathin films are assembled from the repetitive, sequential adsorption of oppositely charged polyelectrolytes from dilute aqueous solution. Recent development in the multilayer systems using hydrogen bonding interactions between polymers exhibits the unique property, a sensitivity to pH change. The films can be selectively stabilized to form micropatterns using inkjet or photo-lithographic methods. The stabilized multilayer films exhibit superb resistance to cell adhesion with long-term durability. The surface of the multilayer film can be functionalized further with specific functional groups such as a cell adhesion peptide ligand. The excellent micropatternability of the films and the tunability of their affinity to cells were combined to study cellular interactions with surfaces. More recently, this H-bonded multilayer was deposited on colloids without flocculation, which shows a great potential in selective drug delivery. In addition, the anti-bacterial coating will be also discussed. |