| 초록 |
Protein cages, including ferritins, viral capsids, and encapsulins, are biomolecule-based supramolecular polymers and attractive candidates for nano-scale cargo delivery vehicles. While the interior surfaces of the protein cages have been used for encapsulation, attachment and synthesis of organic and inorganic materials, their exterior surfaces have been used for multivalent presentations of molecules, including affinity tags, antibodies, fluorophores, carbohydrates, nucleic acids, and peptides, for molecular targeting and hierarchical structure formation. We genetically and chemically modified various types of protein cage nanoparticles to use them as modular delivery nanoplatforms. |
