| 학회 | 한국화학공학회 |
| 학술대회 | 2007년 가을 (10/26 ~ 10/27, 한국과학기술원) |
| 권호 | 13권 2호, p.1649 |
| 발표분야 | 분리기술 |
| 제목 | Economic evaluation of D-,L-mandelic acid separation in SMB(Simulated Moving Bed) chromatography |
| 초록 | SMB(simulated moving bed) is a chromatographic process that, unlike traditional HPLC system, operates continuously without losing the enantiomeric purity of the outlet streams. We performed separation experiments for separating D- and L-form from racemate mandelic acid mixture by using lab-scale SMB unit with 9 operation conditions. The operating conditions were chosen from results simulated by Aspen chromatography as well as batch chromatographic HPLC experiments. The objective of this study is to minimize manufacturing cost. We compared operating costs at 9 operating conditions. Acknowledgement It is supported by BSEP ERC of Inha university as well as KOSEF grant number R01-2005-000-10245-0 |
| 저자 | 이 은, 김인호 |
| 소속 | 충남대 |
| 키워드 | Mandelic acid; Aspen chromatography; SMB chromatography; Economic evaluation |
| 원문파일 | 초록 보기 |
