| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 봄 (04/29 ~ 05/01, BEXCO (부산)) |
| 권호 |
19권 1호 |
| 발표분야 |
나노_포스터 |
| 제목 |
Fluorescent Sensor for Rapid and Ultrasensitive Detection of an anthrax biomarker based on Graphene quantum dot |
| 초록 |
A simple and reliable approach for detecting B. anthracis spores is explored based on the integration of GQDs into a europium (Eu)-macromolecule complex. This novel approach involves anchoring Eu onto GQDs of two different diameters, which provides a change in the fluorescence intensity that varies with the concentration of B. anthracis. Most importantly, the Eu-modified GQDs reported here exhibit an excellent limit of detection (LOD) of 10 pM towards B. anthracis; this concentration is six orders of magnitude smaller than the infectious dose of the spores (60 µM). We also demonstrate excellent specificity towards the B. anthracis spores via measurements of sensitivity in aqueous solutions containing numerous aromatic ligands. The insight into detection properties of GQDs and binding with europium complex may offer an opportunity for the further investigation of biological & medical applications. |
| 저자 |
유재훈, 장정식
|
| 소속 |
서울대 |
| 키워드 |
anthrax; europium; graphene; sensors; quantum dots; graphene quantum dots; GQD
|
| E-Mail |
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