| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
Anti-inflammatory effects in vitro of methanol extraction from Caesalpinia sappan |
| 초록 |
Antioxidant activity and anti-inflammatory effect of Caesalpinia sappan heartwood was studied both by in vitro models. caesalpinia asppanwere extracted with 100% methanol and the fractionated with H2O, n-hexane, ethyl acetate and butyl alcohol to get active fraction. The antioxidant properties of the fractions were determined by several antioxidant methods ; free radical scavenging test (1,1-diphenyl-2-picryl-hydrazyl ; DPPH), reductive potentials method assay. The ethyl acetate fraction of caesalpinia asppan showed strong effects for reductive potential, free radical scaverging at tested concentrations. the active fraction showed anti-inflammatory effects by cytotoxic activity test(MTT) and nitric oxide(NO) assay. The active fraction suppressed nitric oxide(NO) generation in mouse macrophage Raw 264.7 cell stimulated by lipopolysaccharide. |
| 저자 |
송미선, Lok Ranjan Bhatt, 채규윤, 곽경철
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| 소속 |
원광대 |
| 키워드 |
Anti-inflammatory; anti-oxidative; caesalpinia asppan; nitric oxide
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| E-Mail |
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