| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Folate receptor-targeted Quantum Dots for Cancer Detection and Imaging |
| 초록 |
Folic acid (FA) has been utilized for tumor targeting of anticancer drugs via folate receptor (FR)-mediated endocytosis. FR is known to be abundantly expressed in a large fraction of human tumors, but only minimally distributed in normal tissues. Therefore, the FR serves as an excellent tumor marker as well as a functional tumor-specific receptor. Here we propose a novel targeted imaging agent for the detection of tumor by using folic acid-quantum dots. The conjugated quantum dots have water soluble and biocompatible properties. The selective targeting effect of the conjugate was determined by evaluating in vitro cell viability and fluorescent imaging. |
| 저자 |
김준기, 이용규, 김인식, 이경원
|
| 소속 |
충주대 |
| 키워드 |
folic acid; quantum dot; cancer; imaging
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| E-Mail |
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