| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터) |
| 권호 |
34권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Comparison for Micelle Formation of Amphiphilic Star Block Copolymers |
| 초록 |
To compare the micelle formation of amphiphilic star block copolymers, we prepared amphiphilic polyethyleneglycol (PEG) and poly (trimethylene carbonate) (TMC) star block copolymers via ring-opening polymerization of trimethylene carbonate (TMC) monomer initiated at the hydroxyl end group of the core PEG using HCl Et2O as a monomer activator. The amphiphilic nature of the segments of these PEG-b-PTMC star block copolymers gave micelles with a coreshell structure in an aqueous phase. Most of the micelles prepared from amphiphilic PEG-b-PTMC star block copolymers were spherical. With increasing arm number, the mean hydrodynamic diameters of micelles and CMC increased. In conclusion, we found that amphiphilic PEG-b-PTMC star block copolymers is potential hydrophobic drug carriers. Acknowledgements: This study was supported by a grant from MKE (Grant no. 10030022). |
| 저자 |
손진수1, 이상효2, 오재민1, 김재호2, 이봉3, 이해방1, 김문석1
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| 소속 |
1한국화학(연), 2아주대, 3부경대 |
| 키워드 |
micelle; star block copolymers; CMC
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| E-Mail |
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