| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
나노구조제어 및 분석기술 |
| 제목 |
Direct-Write Patterning of a Adeno-Associated Virus on Silicon Oxide Surfaces |
| 초록 |
Dip-Pen Nanolithography(DPN) technique is a useful tool to pattern a various biomolecules such as DNA and proteins on the solid surfaces. However, it is a challenging issue for DPN to generate nanoarrays of high-molecular-weight biomolecules such as a virus and cells, because of their low diffusion rate. In this study, we have coated hydrophilic polyoxazoline polymer on the silicon tip surface through surface polymerization. Using there stamp tip, we have successfully generated nano structures of Cy3-labeled adeno-associated virus(AAV) molecules in a direct-write fashion. The polyoxazoline- coated probe and AAV nanopatterns were characterized by FE-SEM and fluoroscence microscope. |
| 저자 |
윤성훈1, 최동식1, 김경민1, 김홍경2, 임정혁1
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| 소속 |
1충주대, 2충주댜학교 나노고분자공학과 |
| 키워드 |
DPN; nanoarray; virus; patterning; polyoxazoline
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| E-Mail |
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