| 학회 |
한국재료학회 |
| 학술대회 |
2011년 가을 (10/27 ~ 10/29, 신라대학교) |
| 권호 |
17권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Porous Hyaluronic acid-Gelatin loaded Sponge Biphasic Calcium Phosphate Scaffold for Bone Implant Application |
| 초록 |
In this study, hyaluronic acid (HyA) – Gelatin (Gel) hydrogels were prepared at ratio of 15:85 with the goal of obtaining a high uniform porosity and porous biocompatibility scaffold for bone tissue engineering applications. In order to develop a proper scaffold for bone implant application, a HyA-Gel hydrogel loaded in sponge Biphasic Calcium Phosphate (BCP) was prepared. To assay the cytocompatibility and cell behavior on the HyA-Gel hydrogel and HyA-Gel/BCP scaffold, cell attachment and spreading of MSCs seeded on the scaffolds were studied. An invivo study was performed for HyA-Gel/BCP scaffolds after 1 and 3 months implantation. Our results provide a novel and simple method to obtain an adequate scaffold for osteoblast cells and indicate that HyA-Gel hydrogel and HyA-Gel/BCP scaffold could be a good candidate for bone tissue engineering scaffolds. |
| 저자 |
Nguyen Thuy Ba Linh1, Shin Woo Kim2, Young Ki Min3, Hun Mo Yang4, Byong-Taek Lee2
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| 소속 |
1Department of Biomedical Eng. & Mater., 2College of Medicine, 3Soonchunhyang Univ., 4Department of Physiology |
| 키워드 |
Hyaluronic acid; Gelatin; Biphasic Calcium Phosphate; MSCs; Bone implant
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| E-Mail |
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