화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2005년 가을 (10/21 ~ 10/22, 인하대학교)
권호 11권 2호, p.1658
발표분야 고분자
제목 Localized surface plasmon resonance sensing of DNA hybridization on nano-imprint lithography patterns
초록 The DNA hybridization could be readily sensed by gold nano patterned on a glass slide by localized surface plasmon resonance (LSPR) measurement. When maetal nanoparticles are excited by electromagnetic radiation, they exhibit collective oscillations of their conduction electrons known as localized surface plasmon. The wavelength corresponding to the extinction maximum λmax, of the LSPR is highly dependent on the size, shape, and dielectric properties of the metal nanoparticles.
In our work, gold nanopatterns were fabricated using nano-imprint lithography(NIL) which readily lends itself to precision control of features and arbitrary array geometry. The LSPR occurs in the visible and IR regions of the spectrum and can be measured by UV-Vis-IR extinction spectroscopy. LSPR spectroscopy of gold nano-patterned films on an transparent substrate (glass) was shown to be a promising tool for labe-free sensing of DNA hybridization and dehybridization.
저자 정진미, 김사라, 양승만, 정희태
소속 한국과학기술원 생명화학공학과
키워드 nano imprint ilthography; surface plasmon resonance; DNA hybridization
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