| 초록 |
In this study, the scaffold was prepared by sequential bi-layer electrospinning on rotating mandrel-type collector. The tubular scaffold are composed of polyurethane(PU)- Polycaprolactone(PCL) fibrous outer-layer and Polycaprolactone (PCL)- polyethylene glycol (PEG) fibrous inner layer. Scaffolds were fabricated successfully for electrosppining technology. The detail microstructure and material properties, tensile and bust strength, contact angle and biocompatibility were investigated and compared with those monolithic of PCL, and PCL-PEG. The other physical properties were examined by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR) and X-ray Diffraction (XRD). In vitro experiment was done by studying of cytotoxicity using MTT assay, and immuneflourescene for cell behaviour. |
