| 초록 |
The hydrogel has been studied for various applications including controlled drug delivery, tissue engineering, micro-scale actuators and microfluidic flow control. In this study, we present a hydrogel actuator consisting of two different layers with significantly different stiffness and capacities to uptake water in response of the environments. This multi-layered hydrogel actuator was prepared by assembling a bi-layered hydrogel, in which each layer consisted of PEGDA with different environment-responsive molecules and their concentrations. This study examines the effects of the multi-layered hydrogel tweezer on stimulating and regulating tumor cell cluster of the morphology, growth rates, and proangiogenic growth factor production. |
