화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 생물공학_포스터
제목 Autotrophic astaxanthin production of Haematococcus pluvialis via the heat stress-driven Haber-Weiss reaction
초록 Photoautotrophic astaxanthin production of Haematococcus pluvialis has a variety of advantages of preventing bacterial contamination and augmenting astaxanthin titer and CO2 conversion. Although multiple adverse conditions to implement an increment in astaxanthin production were previously reported, high temperatures were not a feasible stress for efficacious photoautotrophic induction in our work. Because the capacity of carotenogenesis was highly depressed by the less reactive oxygen species (LROS; O2- and H2O2) excessively generated at high temperatures (30-36°C) in contrast to the more reactive oxygen species (MROS; O2 and OH•). This inefficient astaxanthin production was resolved by accelerating Iron-catalyzed Haber-Weiss reaction to convert LROS into MROS, facilitating lipid peroxidation. The heat stress-driven Haber Weiss reaction will improve the photoautotrophic astaxanthin production from H. pluvialis under high temperatures via the ratio control between Iron ions and LROS.
저자 곽호석, 홍민의, 심상준
소속 고려대
키워드 Astaxanthin; Haemaotococcus pluvialis; Haber-Weiss reaction; Reactive oxygen species
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