| 학회 | 한국고분자학회 |
| 학술대회 | 2004년 가을 (10/08 ~ 10/09, 경북대학교) |
| 권호 | 29권 2호, p.364 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Biodegradable Polymeric Materials for Hard Tissue Fixation |
| 초록 | Biodegradable polymeric internal fixation devices are superior to metallic or ceramic fixation devices in many aspects, e. g., no need for the second removal operation, no corrosion problems, and safe reduction of the fracture. Poly-L-lactic acid (PLLA) is one of the most widely used biodegradable polymers and has various applications for internal fixation devices of lower strength materials. In a previous study we reported enhancement of mechanical properties of PLLA by solid-state extrusion and PLLA fixation devices with high strength. The purpose of this study is development of fixation devices with flexibility. ξ-Caprolacton appears to be a suitable comomomer for the preparation of a diversified family of copolymers with mechanical properties ranging from elastomeric to rigid. In this study L-Lactide/ξ-Caprolacton copolymers(PLCL) with minor ξ-Caprolacton contents were investigated. Vacuum compression molding and solid-state extrusion technique were employed for the minimization of molecular degradation and the improvement of mechanical properties of PLCL . Billets machined out from the vacuum compression-molded PLCL were solid-state extruded through circular and rectangular dies to produce rods and plates. Extrusion was performed at solid-state and draw ratio and drawing rate were varied. On the basis of the measurements of the orientation, crystallinity, mechanical property of extruded PLCL, effects of initial billet morphology, draw ratio, drawing rate, contents of ξ-Caprolacton on the mechanical properties of PLCL were discussed. figure 1. Flexural stress-strain curves of solid-state extrudated PLLA rods ( 3.5 mm ) and plates ( 1 mm X 8 mm ). |
| 저자 | 이선영1, 김수현1, 김영하1, 김성헌1, 김병수2 |
| 소속 | 1한국과학기술(연), 2한양대 |
| 키워드 | PLCL; Flexible; Biodegradable; Bone Fixation Implant |
