| 초록 |
Designing a 3-D ideal scaffold has been one of the main issues in biomaterials and tissue engineering. To fabricate a scaffold to fit the needs of individual patients, various manufacturing methods have been suggested. Rapid prototyping(RP) technology of these methods meets closely the requirement by mimic structures that were obtained from computer tomography. However, one main disadvantage of the RP-processed scaffolds is the smooth surface of the strands, which is unfavorable enough conditions of initial cell attachment. To overcome this problem, we suggest a new RP-technology to fabricate hierarchical structure ranging from several microsize to nanosize. In addition, the effects of variables of the scaffold structure including strand diameter and distance were examined with respect to the cell attachment and proliferation. |
