| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
고분자합성-구조제어중합 |
| 제목 |
Synthesis of thermo-responsive poly(N-vinyl caprolactam)-b-poly(ε-caprolactone) block copolymers by a combination of ROP and RAFT polymerization |
| 초록 |
Amphiphilic block copolymers composed of biocompatible hydrophilic and hydrophobic blocks have been attracted much attention as nano-sized carriers for poorly water-soluble drugs. In this study, biocompatible and thermo-responsive poly(N-vinyl caprolactam)-b-poly(ε-caprolactone) (PVCL-b-PCL) diblock copolymers were synthesized by a combination of ROP and RAFT polymerization. PCL synthesized by ROP was modified into PCL macro-chain transfer agent (PCL-CTA), and then RAFT polymerization of N-vinyl caprolactam was conducted using PCL-CTA. This method was found to be very useful to produce well-defined PVCL-b-PCL diblock copolymers. The micelles of PVCL-b-PCL diblock copolymers exhibited reversible thermo-responsive behaviors at ~30 oC. |
| 저자 |
유영창, 기보람, 이동욱, 강현욱, 육지호
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| 소속 |
인하대 |
| 키워드 |
ROP; RAFT; PCL-b-PVCL; amphiphilic block copolymer; LCST
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| E-Mail |
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