| 초록 |
Autotrophic culture offers a promising strategy for high yield of astaxanthin production without supplying organic carbon source in H. pluvialis. However, the lower astaxanthin productivity than the heterotrophic culture needs to be improved. SC (second carotenoid) synthesis could be associated with the generation of ROS. Notably, overproduction and accumulation of intracellular O2- delayed the carotenogenesis and decreased the astaxanthin productivity, whereas the rapid conversion of overproduced O2- to OH· by Haber-Weiss Fenton reaction improved the productivity. Above all, the combination of high temperature condition (30~40°C), and Fenton reaction showed the remarkable astaxanthin production under photoautotrophic condition. These results indicate the explosive supply of superoxide under stress-induced condition followed by the rapid conversion of O2- to OH· can be an effective solution for the acceleration and improvement of photoautotrophic astaxanthin production. |
