화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO))
권호 23권 1호
발표분야 정밀화학_포스터
제목 Application of aluminum amide reagents in the Synthesis of 5-Amino-substituted 1,2,4-oxadiazoles
초록 1,2,4-oxadiazoles is biological activities such as human tryptase inhibitory activity, antitrypanosomal activity, genotoxic activity, peptide inhibitory activity and antihyperglycemic activity. We synthesized of 1,2,4-oxadiazoles from azidoximes with using via Staudinger reaction followed by aza-Wittig reaction. In this work, 1,2,4-oxadiazoles were synthesized using smart cleavage reaction between 5-Amino-substituted 1,2,4-oxadiazoles and aluminum amide reagents, in good yields.
저자 Amarbayasgalan Nergui, 이상협
소속 대구가톨릭대
키워드 Oxadiazoles; Aluminum amides reagents
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