학회 | 한국공업화학회 |
학술대회 | 2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
권호 | 23권 1호 |
발표분야 | 정밀화학_포스터 |
제목 | Application of aluminum amide reagents in the Synthesis of 5-Amino-substituted 1,2,4-oxadiazoles |
초록 | 1,2,4-oxadiazoles is biological activities such as human tryptase inhibitory activity, antitrypanosomal activity, genotoxic activity, peptide inhibitory activity and antihyperglycemic activity. We synthesized of 1,2,4-oxadiazoles from azidoximes with using via Staudinger reaction followed by aza-Wittig reaction. In this work, 1,2,4-oxadiazoles were synthesized using smart cleavage reaction between 5-Amino-substituted 1,2,4-oxadiazoles and aluminum amide reagents, in good yields. |
저자 | Amarbayasgalan Nergui, 이상협 |
소속 | 대구가톨릭대 |
키워드 | Oxadiazoles; Aluminum amides reagents |