화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔)
권호 12권 1호, p.171
발표분야 공정시스템
제목 WebCell: an integrated web environment for modeling and simulation of cellular networks
초록 WebCell provides an integrated simulation environment for managing quantitative and qualitative information on cellular networks, and for interactively exploring their steady-state and dynamic behaviors over the web. A user-friendly web interface allows users to efficiently create, visualize, simulate and store their reaction network models, thereby facilitating kinetic modeling and simulation of biological systems of interest. Supported analysis methods for such models include structural pathway analysis, MCA, conservation analysis and dynamic simulation. In addition, a variety of model collections publicly available have been compiled to provide comprehensive implications for cellular dynamics of the models. Thus, this comprehensive, web-accessible and integrative system not only serves the educational demonstration site of publicly available kinetic models but also provides the customized modeling environment for quantitatively analyzing the cellular system. This work was supported by the Korean Systems Biology Research Program (M10309020000-03B5002-00000) of the MOST and by the BK21 project and by Center for Ultramicrochemical Process Systems sponsored by KOSEF.
저자 윤좌문1, 이동엽2, 조아연3, 이상엽1, 박선원1
소속 1한국과학기술원 생명화학공학과, 2Department of Chemical and Biomolecular Engineering, 3싱가폴국립대
키워드 web-based application; kinetic modeling and simulation; cellular dynamics; SBML; systems biology
E-Mail
원문파일 초록 보기