| 학회 |
한국화학공학회 |
| 학술대회 |
2008년 봄 (04/23 ~ 04/25, 제주ICC) |
| 권호 |
14권 1호, p.371 |
| 발표분야 |
분리기술 |
| 제목 |
Chiral selectivity of racemic mandelic acid by contact-AFM modified with 4-amino-L-phenylalanine |
| 초록 |
In the present study, we have examined the difference in molecular interaction of two enantiomers of racemic Mandelic acid by Contact – AFM with tip modified with 4-amino-L-phenylalanine. The results showed that there is no chiral selectivity of two enantiomers of Mandelic acid with the unmodified tip of contact-AFM. In the case of the modified tip, the interaction of L-mandelic acid and 4-amino-L-phenylalanine with the adhesive force of 159 pN comparing to 90 pN of D-mandelic acid have provided the strong evidence of enantiomeric selectivity of L-phenylalanine with L-mandelic acid over than D-mandelic acid. In the other hand, the heat fusion of crystals representing the host-guest interaction was also agreed with adhesive force data with enthalpy of L-mandelic.L-phenylalanine 167kJ/mol and D-mandelic.L-phenylalanine 117kJ/mol. Consequently, the results indicated that 4-amino-L-phenylalanine could be applied to predict the chiral separation of racemic Mandelic acid. |
| 저자 |
팜시안헝1, 김인호2, 장상목3, 김종민3, 김우식1
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| 소속 |
1경희대, 2충남대, 3동아대 |
| 키워드 |
4-amino-L-phenylalanine; Chiral selectivity
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| E-Mail |
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| 원문파일 |
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